李连之老师简介

 

hxhgxy.lcu.edu.cn

博士/教授

 

TEL/ 0635-8239656

EMAIL/ lilianzhi@lcu.edu.cn

    出生日期/ 1963.4.13

 

籍     贯/山东茌平

科研方向/无机化学

 
       讲授课程:

 

《无机及分析化学》(本科生);《生物无机化学》(研究生及本科生选修课)

教育经历:

1981.9-1985.7  山东师范大学化学系本科生

1988.9-1991.7  北京医科大学药学院(现北大医学部)硕士生

1995.9-1998.7  南开大学化学系博士生

1999.3-2001.6  复旦大学化学系博士后

科研项目

1.      神经红蛋白的化学生物学基础及其结构、机理与功能关系,国家自然科学基金(No. 20471025)

2. 新型抗糖尿病药物钒配合物的合成、结构与活性及作用机理研究,山东省自然科学基金(No. Y2004B02)

3. 神经红蛋白的结构、性质与功能关系研究,南京大学配位化学国家重点实验室开放基金

4. 新型人工金属蛋白/金属酶的分子构建、性质与催化功能,国家自然科学基金(No. 21142003)

5. 基于神经红蛋白肽链的新颖金属蛋白/酶的分子设计和性能研究,山东省自然科学基金 (No. ZR2011BL002)

获奖情况

论著一览

1.      Qiang Wei, Jianfang Dong, Peiran Zhao, Manman Li, Fengling Cheng, Jinming Kong, Lianzhi Li*, DNA binding, BSA interaction and SOD activity of two new nickel(II) complexes with glutamine schiff base ligands, J. Photochem. Photobiol. B, 2016, 161, 355-367.

2.      Hongyan Liu, Qiong Guo, Jianfang Dong, Qiang Wei, Han Zhang, Xubo Sun, Cuicui Liu, Lianzhi Li*, Synthesis, crystal structure and interaction with DNA and BSA of a chromium(III) complex with naph-gly Schiff base and 1,10-phenanthroline. J. Coord. Chem., 2015, 68(6), 1040-1053.

3. Shanshan Zhai, Qiong Guo, Jianfang Dong, Tao Xu, Lianzhi Li*, An oxovanadium(IV) complex of an L-serine Schiff base and 1,10-phenanthroline: synthesis, crystal structure, and DNA and albumin-binding properties, Transition Met. Chem., 2014, 39:271–280.

4. Qiong Guo, Lianzhi Li*, Jianfang Dong, Hongyan Liu, Tao Xu, Jinghong Li, Synthesis, crystal structure and interaction of L-valine Schiff base divanadium(V) complex containing a V2O3 core with DNA and BSA, Spectrochim. Acta A: 2013, 106, 155-162.

5. Erqiong Wang, Zhaoyong Xi, Yan Li, Lianzhi Li, Linhong Zhao, Guolin Ma*, Yangzhong Liu*, Interaction between Platinum Complexes and the C‑Terminal Motif of Human Copper Transporter 1, Inorg. Chem. 2013, 52, 6153−6159.

6. Yan Li, Lianzhi Li*, Xuewei Pu, Guolin Ma, Erqiong Wang, Jinming Kong, Zhipeng Liu and Yangzhong Liu, Synthesis of a ratiometric fluorescent peptide sensor for the highly selective detection of Cd2+, Bioorg. Med. Chem. Lett., 2012, 22, 4014-4017.

7. Guolin Ma, Fan Huang, Xuewei Pu, Liangyuan Jia, Tao Jiang, Lianzhi Li, Yangzhong Liu*, Identification of [PtCl2(phen)] binding modes in amyloid-b peptide and the mechanism of aggregation inhibition, Chem. Eur. J.,2011, 17, 11657-11666.

8. Lianzhi Li*, Zhenghua Guo, Qingfu Zhang, Tao Xu, Daqi Wang, An unexpected oxovanadium(IV) complex with in situ generated lactone ligand: Synthesis, crystal structure and DNA-binding property, Inorg. Chem. Commun., 2010, 13, 1166-1169.

9. Jia Xu, Lianzhi Li, Guowei Yin, Haili Li, Weihong Du*, Ligand orientation of human neuroglobin obtained from solution NMR and molecular dynamics simulation as compared with X-ray crystallography, J. Inorg. Biochem., 2009, 103, 1693-1701.

10. Zhao Chao, Li Lianzhi*, Wang Li, Ji Haiwei. Circular dichroism spectral studies on the recombinant human neuroglobin. Chinese Sci. Bull., 2006, 51(21), 2581-2585.

11. Lian-Zhi Li*, Chao Zhao, Tao Xu, Hai-Wei Ji, Yan-Hong Yu, Guang-Qiang Guo, Hui Chao. Synthesis, crystal structure and nuclease activity of a Schiff base copper(II) complex. J. Inorg. Biochem., 2005, 99 (5), 1076-1082.

3.   相关成果